It all begins with one basic rule: Draw one card, play one card. You start with a hand of three cards, add the card you drew to your hand, and then choose one card to play, following the directions written on your chosen card. As cards are drawn and played from the deck, the rules of the game change from how many cards are drawn, played, or even how many cards you can hold at the end of your turn. 

Star Trek: DS9 Fluxx Card List